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Corrigendum for Jelson et al., Am J Physiol Regul Integr Comp Physiol 285 (3) 682-689.
Am J Physiol Regul Integr Comp Physiol 286: R232, 2004; doi:10.1152/ajpregu.00610.2003
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Volume 54, September 2003

Pages R682-R689: Jelson, Gregory S., Gina M. DeMasi, Kristen L. Sager, and Jean C. Hardwick. "Modulation of guinea pig intrinsic cardiac neurons by prostaglandins" (http://ajpregu.physiology.org/cgi/content/abstract/285/3/R682). PGE2 was incorrectly labeled as PGD2 in Fig. 2, B and D, and Fig. 4B. The correct figures and original legends appear below.



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Fig. 2. Prostaglandin-induced changes in membrane potential and AHP. PGD2 and PGE2 were applied by local pressure ejection (1 s, 10-4 M). Both prostaglandins produced a biphasic membrane response (A and B) of a brief hyperpolarization followed by a more prolonged depolarization. In addition, action potentials collected in these same cells before and just after prostaglandin application showed a decrease in AHP duration after PGD2 or PGE2 application. Resting membrane potentials were A and C, -50 mV; B and D, -40 mV.

 


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Fig. 4. Effects of bath perfusion of PGD2 and PGE2 on the membrane response. PGD2 and PGE2 were perfused over the cells at a concentration of 1 µM for 30 s. There was no measurable change in membrane potential with PGD2 perfusion (A). However, PGE2 perfusion produced a biphasic membrane response similar to the response observed after local pressure application. Solid lines indicate the duration of the prostaglandin perfusion. Resting membrane potentials were A, -52 mV; and B, -65 mV.

 





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