Volume 277, October 1999 Volume 46, October 1999

Pages R1013-R1019: Theodoros Vassilakopoulos, Spyros Zakynthinos, and Charis Roussos. "Strenous resistive breathing induces proinflammatory cytokines and stimulates the HPA axis in humans."

Figure 1 on R1015 appeared with incorrectly labeled axes; the correct figure is below.

The following sentences contained incorrectly cited references; correct citations appear in bold.

R1017, left column, fifth line from bottom: "Previous studies indicate that both IL-1 and IL-6 are potent stimulants of the HPA axis (8, 25, 26), exhibiting significant synergism (8, 28, 32)."

R1017, right column, seventh line from bottom: "In fact, global depletion of small afferent fibers (by repeated systemic treatment with capsaicin) inhibits the plasma ACTH response to intravenous IL-1 (49)."

R1018, left column, second line from top: "This would be analogous to the role of small vagal afferent activation in eliciting hypothalamic and HPA axis responses after intraperitoneal injection of IL-1 in animals, which are abolished after subdiaphragmatic transection of the vagus (45)."

View larger version (17K): [in this window] [in a new window]   Fig. 1.   Mean plasma level of interleukin-1 (IL-1; A), interleukin-6 (IL-6; B), -endorphin (C), and ACTH (D) at rest (point R), at point at which subjects could not generate target maximum inspiratory pressure (point F), and at end of resistive breathing (point E). Vertical bars are ±SE. *Statistically significant difference (P < 0.05) from point R; #statistically significant difference (P < 0.05) from point F; +statistically significant difference (P < 0.01) from the moderate-load run. Closed symbols, high-load run; open symbols, moderate-load run.