AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 274: R1111-R1118, 1998;
0363-6119/98 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Morita, H.
Right arrow Articles by Lee, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Morita, H.
Right arrow Articles by Lee, K.
Vol. 274, Issue 4, R1111-R1118, April 1998

Role of the liver in long-term control of drinking behavior, Na+ balance, and arterial pressure in Dahl rats

Hironobu Morita, Kiyoshi Tsunooka, Masanobu Hagiike, Osamu Yamaguchi, and Ken Lee

Department of Physiology, Gifu University School of Medicine, Gifu 500-8705, Japan

The role of postabsorptive mechanisms in long-term control of drinking behavior, Na+ balance, and arterial pressure was examined in Dahl salt-sensitive (DS) and salt-resistant (DR) rats. NaCl (0.15 M) was infused (0.5 ml/h) into either the inferior vena cava (IVC) or the portal vein (PV) for 7 days, and then 1.5 M NaCl was infused for 10 days. During 1.5 M infusion, the IVC group retained more Na+ than the PV group. Furthermore, in DS rats, mean arterial pressure was higher in the IVC group than in the PV group. Regardless of the strain and infusion route, 1.5 M infusion had no effect on volume of daily saline consumption. However, when the data for light and dark periods were analyzed separately, dark period saline consumption in the PV group was decreased by 1.5 M infusion but was not changed in the IVC group. These results indicate that, in Dahl rats, the postabsorptive mechanism plays a significant role in controlling long-term saline drinking behavior and Na+ balance and has a significant role in controlling arterial pressure in DS, but not DR, rats.

hepatoportal sodium-sensitive mechanism; hypertonic saline infusion; portal vein; water consumption; saline consumption


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
S. N. Orlov and A. A. Mongin
Salt-sensing mechanisms in blood pressure regulation and hypertension
Am J Physiol Heart Circ Physiol, October 1, 2007; 293(4): H2039 - H2053.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
Y. Tsuchiya, S. Nakashima, Y. Banno, Y. Suzuki, and H. Morita
Effect of high-NaCl or high-KCl diet on hepatic Na+- and K+-receptor sensitivity and NKCC1 expression in rats
Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2004; 286(3): R591 - R596.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
T. M. Gotoh, N. Fujiki, T. Matsuda, S. Gao, and H. Morita
Roles of baroreflex and vestibulosympathetic reflex in controlling arterial blood pressure during gravitational stress in conscious rats
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2004; 286(1): R25 - R30.
[Abstract] [Full Text]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
H. Morita, N. Fujiki, T. Miyahara, K. Lee, and K. Tanaka
Hepatoportal bumetanide-sensitive K+-sensor mechanism controls urinary K+ excretion
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2000; 278(5): R1134 - R1139.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online