AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 262: R235-R240, 1992;
0363-6119/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shinoda, H.
Right arrow Articles by Stern, P. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shinoda, H.
Right arrow Articles by Stern, P. H.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 262, Issue 2 235-R240, Copyright © 1992 by American Physiological Society

ARTICLES

Diurnal rhythms in Ca transfer into bone, Ca release from bone, and bone resorbing activity in serum of rats

H. Shinoda and P. H. Stern
Department of Pharmacology, Tohoku University School of Dentistry, Sendai, Japan.

To characterize diurnal rhythms in calcium transfer in and out of bone, rats were adapted to a 12:12 h light-dark illumination program (with light from 0600 to 1800 h). For studies of deposition, rats were injected with 45CaCl2 at 0300, 0700, 1100, 1500, 1900 or 2300 h and killed with chloroform inhalation 60 min later, and radioactivity was determined in tibia and mandibular incisor. Peak deposition occurred at 2400 h, with a nadir at 1200 h. For studies of radionuclide release, rats were prelabeled with 45CaCl2 for 6 days and serum obtained from the tail at 4-h intervals. 45Ca and specific activity were maximal around 1200-1600 h and lowest late in the dark period. To determine the role of humoral factor(s), fetal rat limb bones were cultured in media prepared with sera from light-dark-adapted rats. Activity was maximal in serum collected at 0800 h and minimal at 1600 h. Heat inactivation at 100 degrees C for 5 min eliminated the difference between the peak and nadir. The results suggest that a heat-sensitive humoral factor(s) regulates diurnal rhythms in calcium metabolism.


This article has been cited by other articles:


Home page
 J. Orthod.Home page
T. Kameyama, Y. Matsumoto, H. Warita, and K. Soma
Inactivated periods of constant orthodontic forces related to desirable tooth movement in rats
J. Orthod., March 1, 2003; 30(1): 31 - 37.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online