AJP - Regu Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 252: R1158-R1164, 1987;
0363-6119/87 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Farber, J. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Farber, J. P.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 252, Issue 6 1158-R1164, Copyright © 1987 by American Physiological Society

ARTICLES

Expiratory effects of cerebellar stimulation in developing opossums

J. P. Farber

Positive-pressure breathing (PPB) causes expiratory activation of abdominal (ABD) and intercostal (IC) muscles in anesthetized opossums. Developmentally these responses begin to appear at about the 30th postnatal day and become prevalent over the next 3-4 wk. The purpose of the present study was to examine effects of constant-current cerebellar stimulation, applied over a single breath, on respiratory timing and expiratory electromyogram (EMG) activity in ABD and IC muscles during PPB in anesthetized opossums from 30-35 days of age to weaning. Electrode placements in the region of the deep cerebellar nuclei showed strong expiration-phased effects. For animals showing expiratory activation of both ABD and IC muscles during PPB, the response at low-current density consisted of suppression of the IC and ABD EMGs; relative inhibition often differed, with reduction of the ABD EMG being greater than for IC muscles. In animals of all ages tested, cerebellar stimulation prolonged the expiratory phase of the stimulated breath. Frequency of cerebellar stimulation needed to achieve maximum prolongation of the breath was significantly lower for younger vs. older animals. Pathways from deep cerebellar nuclei may differentially influence the activity of motor groups with comparable respiratory functions; this may be related to a cerebellar function of coordinating respiratory and nonrespiratory (i.e., movement and posture) functions of specific motor groups.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
F. Xu and D. T. Frazier
Modulation of respiratory motor output by cerebellar deep nuclei in the rat
J Appl Physiol, September 1, 2000; 89(3): 996 - 1004.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
F. Xu, D. T. Frazier, Z. Zhang, D. M. Baekey, and R. Shannon
Cerebellar modulation of cough motor pattern in cats
J Appl Physiol, August 1, 1997; 83(2): 391 - 397.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
F. Xu and D. T. Frazier
Respiratory-related neurons of the fastigial nucleus in response to chemical and mechanical challenges
J Appl Physiol, April 1, 1997; 82(4): 1177 - 1184.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online