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Am J Physiol Regul Integr Comp Physiol 252: R419-R422, 1987;
0363-6119/87 $5.00
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AJP - Regulatory, Integrative and Comparative Physiology, Vol 252, Issue 2 419-R422, Copyright © 1987 by American Physiological Society

ARTICLES

In vivo metabolic activity of hamster suprachiasmatic nuclei: use of anesthesia

W. J. Schwartz

In vivo glucose utilization was measured in the suprachiasmatic nuclei (SCN) of Golden hamsters using the 14C-labeled deoxyglucose technique. A circadian rhythm of SCN metabolic activity could be measured in this species, but only during pentobarbital sodium anesthesia when the surrounding background activity of adjacent hypothalamus was suppressed. Both the SCN's metabolic oscillation and its time-keeping ability are resistant to general anesthesia.




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