AJP - Regu Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Regul Integr Comp Physiol 249: R228-R236, 1985;
0363-6119/85 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yokota, S. D.
Right arrow Articles by Dantzler, W. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yokota, S. D.
Right arrow Articles by Dantzler, W. H.

AJP - Regulatory, Integrative and Comparative Physiology, Vol 249, Issue 2 228-R236, Copyright © 1985 by American Physiological Society

ARTICLES

Renal function in sea snakes. I. Glomerular filtration rate and water handling

S. D. Yokota, S. Benyajati and W. H. Dantzler

Renal clearance studies were performed on anesthetized sea snakes (Aipysurus laevis) under various salt and volume loads. The median values for the control glomerular filtration rate (GFR) and urine flow rate (V) were 0.78 and 0.11 ml X kg-1 X h-1, respectively. Acute salt loading with 1 mol/l NaCl significantly increased V to 0.68 ml X kg-1 X h-1, whereas acute water loading significantly decreased GFR to 0.17 ml X kg-1 X h-1. Acute loading with either isosmotic NaCl or seawater did not significantly alter either V or GFR. Chronic loading with water or seawater by intraperitoneal injection significantly increased both GFR and V. No consistent relationship between plasma osmolality and GFR was observed. Instead a threshold-type relationship existed between GFR and plasma K concentration. Within each treatment group, high plasma K concentrations were correlated with low GFRs. There was an abrupt increase in GFR at low plasma K concentrations, the inflection point ranging from 2.5 to 4 mmol/l K depending on the experimental treatment. A curvilinear relationship existed between V and GFR; as GFR increased, V approached a maximal limiting value. At low GFRs (less than 0.2 ml X kg-1 X h-1), V often exceeded GFR, indicating net fluid secretion that was correlated with net Na movement. In addition, there was an inverse relationship between urine-to-plasma osmolality ratio and V. At low values of V, urine osmolalities modestly exceeded those of the plasma. Overall, renal function of A. laevis appears to be adapted to conserve water.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
S. L. Zimmerman, J. Frisbie, D. L. Goldstein, J. West, K. Rivera, and C. M. Krane
Excretion and conservation of glycerol, and expression of aquaporins and glyceroporins, during cold acclimation in Cope's gray tree frog Hyla chrysoscelis
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2007; 292(1): R544 - R555.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online