AJP - Regulatory, Integrative and Comparative Physiology, Vol 232, Issue 5 185-R189, Copyright © 1977 by American Physiological Society
Effect of volume expansion and veratrine on salt gland secretion in the goose
I. H. Zucker, C. Gilmore, J. Dietz and J. P. Gilmore
The influence of acute intravascular volume expansion on salt gland
secretion of conscious, adult geese was investigated. The intravenous
administration of 5% dextran in Krebs-bicarbonate-Ringer solution in an
amount equivalent to 30% of the estimated blood volume caused a transient
but highly significant increase in salt gland secretion independent of
changes in plasma osmolality or sodium concentration. Intravenous veratrine
(60 microng) caused a similar increase in salt gland secretion only when
administered after the volume load. Intravenous 5% NaCl always caused a
prolonged and significant increase in salt gland secretion which was not
potentiated by veratrine. Volume expansion and hypertonic saline caused a
significant tachycardia while veratrine caused a significant bradycardia.
It is concluded that a volume component may contribute to the initiation of
salt gland secretion in the goose and that the peripheral receptor involved
is most likely vascular in origin.
